Search results for " 92D10"
showing 3 items of 3 documents
Importance sampling for Lambda-coalescents in the infinitely many sites model
2011
We present and discuss new importance sampling schemes for the approximate computation of the sample probability of observed genetic types in the infinitely many sites model from population genetics. More specifically, we extend the 'classical framework', where genealogies are assumed to be governed by Kingman's coalescent, to the more general class of Lambda-coalescents and develop further Hobolth et. al.'s (2008) idea of deriving importance sampling schemes based on 'compressed genetrees'. The resulting schemes extend earlier work by Griffiths and Tavar\'e (1994), Stephens and Donnelly (2000), Birkner and Blath (2008) and Hobolth et. al. (2008). We conclude with a performance comparison o…
Probabilities of large values for sums of i.i.d. non-negative random variables with regular tail of index $-1$
2021
Let $\xi_1, \xi_2, \dots$ be i.i.d. non-negative random variables whose tail varies regularly with index $-1$, let $S_n$ be the sum and $M_n$ the largest of the first $n$ values. We clarify for which sequences $x_n\to\infty$ we have $\mathbb P(S_n \ge x_n) \sim \mathbb P(M_n \ge x_n)$ as $n\to\infty$. Outside this regime, the typical size of $S_n$ conditioned on exceeding $x_n$ is not completely determined by the largest summand and we provide an appropriate correction term which involves the integrated tail of $\xi_1$.
Analysis of DNA sequence variation within marine species using Beta-coalescents
2013
We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit so-called shallow gene genealogies, potentially due to extreme reproductive behaviour, e.g. via Hedgecock's "reproduction sweepstakes". Besides the data analysis, in particular the inference of mutation rates and the estimation of the (real) time to the most recent common ancestor, we briefly address the question whether the genealogies might be adequately described by so-called Beta coalescents (as opposed to Kingman's coalescent), allowing multiple mergers of genealogies. The choice of the underlying…